Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the CellSearch System

20071,331 citationsJournal Article

Authors

Sabine Riethdorf · University Medical Center Hamburg-Eppendorf

Herbert A. Fritsche · The University of Texas MD Anderson Cancer Center

Volkmar Müller · University Medical Center Hamburg-Eppendorf

Thomas Rau · University Medical Center Hamburg-Eppendorf

Christian Schindlbeck · Ludwig-Maximilians-Universität München

Brigitte Rack · Ludwig-Maximilians-Universität München

Wolfgang Janni

Abstract

The CellSearch system enables the reliable detection of CTCs in blood and is suitable for the routine assessment of metastatic breast cancer patients in the clinical laboratory. Blood samples should be shipped at room temperature and CTC counts are stable for at least 72 h.

Topics & Keywords

Cancer Cells and Metastasis Microfluidic and Bio-sensing Technologies Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 3, pp. 920-928

DOI: 10.1158/1078-0432.ccr-06-1695

Field-Weighted Citation Impact: 18.31