A new route to dithia- and thiaoxacyclooctynes via Nicholas reaction

201424 citationsJournal Article

Authors

Tobias Hagendorn · Karlsruhe University of Education

Stefan Bräse · Kentucky imaging Technologies (United States)

Abstract

By using the Nicholas reaction we managed to design a concise synthesis that only uses three steps to build the eight-membered ring. It was also possible to functionalize said alkyne with a fluorophore.

Topics & Keywords

Click Chemistry and Applications Sulfur-Based Synthesis Techniques Cyclopropane Reaction Mechanisms

Publication Details

Published in: RSC Advances

Volume 4, Issue 30, pp. 15493-15495

DOI: 10.1039/c4ra01345j

Field-Weighted Citation Impact: 1.27

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A new route to dithia- and thiaoxacyclooctynes via Nicholas reaction

Authors

Abstract

Topics & Keywords

Publication Details