Contribution of Tonic Chemoreflex Activation to Sympathetic Activity and Blood Pressure in Patients With Obstructive Sleep Apnea

1998416 citationsJournal Articlebronze Open Access

Authors

Krzysztof Narkiewicz · Iowa Diabetes and Endocrinology Research Center

Philippe J. H. van de Borne · Iowa Diabetes and Endocrinology Research Center

Nicola Montano · Iowa Diabetes and Endocrinology Research Center

Mark Eric Dyken · Iowa Diabetes and Endocrinology Research Center

Bradley G. Phillips · Iowa Diabetes and Endocrinology Research Center

Virend K. Somers · Iowa Diabetes and Endocrinology Research Center

Abstract

Tonic activation of excitatory chemoreflex afferents may contribute to increased efferent sympathetic activity to muscle circulation in patients with OSA.

Topics & Keywords

Obstructive Sleep Apnea Research Heart Rate Variability and Autonomic Control Neuroscience of respiration and sleep

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 97, Issue 10, pp. 943-945

DOI: 10.1161/01.cir.97.10.943

Field-Weighted Citation Impact: 3.53