In Vivo Evidence of Angiogenesis Induced by Transcription Factor Ets-1

2004101 citationsJournal Articlebronze Open Access

Authors

Naotaka Hashiya · Kaw Nation

Nobuo Jo · Kaw Nation

Motokuni Aoki · Kaw Nation

Kunio Matsumoto · Kaw Nation

Toshikazu Nakamura · Kaw Nation

Yasufumi Sato · Kaw Nation

Nahoko Ogata · Kaw Nation

Abstract

The present study demonstrated that ets-1 regulated angiogenesis through the induction of angiogenic growth factors (VEGF and HGF). Overexpression of ets may provide a new therapeutic strategy to treat peripheral arterial disease.

Topics & Keywords

Angiogenesis and VEGF in Cancer Cell Adhesion Molecules Research Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 109, Issue 24, pp. 3035-3041

DOI: 10.1161/01.cir.0000130643.41587.db

Field-Weighted Citation Impact: 2.87