Inflammatory Biomarkers, Hormone Replacement Therapy, and Incident Coronary Heart Disease

2002674 citationsJournal Article

Authors

Aruna D. Pradhan

JoAnn E. Manson · Harvard University Press

Jacques E. Rossouw · National Institutes of Health

David S. Siscovick · University of Washington

Charles P. Mouton · The University of Texas Health Science Center at San Antonio

Nader Rifai · Harvard University Press

Robert B. Wallace

Rebecca D. Jackson

Abstract

These prospective findings indicate that CRP and IL-6 independently predict vascular events among apparently healthy postmenopausal women and that HRT increases CRP. However, use or nonuse of HRT had less importance as a predictor of cardiovascular risk than did baseline levels of either CRP or IL-6.

Topics & Keywords

Menopause: Health Impacts and Treatments Adipokines, Inflammation, and Metabolic Diseases Estrogen and related hormone effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 288, Issue 8, pp. 980-980

DOI: 10.1001/jama.288.8.980

Field-Weighted Citation Impact: 35.98