PTX3, A Prototypical Long Pentraxin, Is an Early Indicator of Acute Myocardial Infarction in Humans

2000423 citationsJournal Article

Authors

Giuseppe Peri · University of Brescia

Martino Introna · University Hospitals Parma Medical Center

Domenico Corradi · Azienda Ospedaliera Ospedale Civile di Legnano

Giuseppe Iacuitti · University of Brescia

Stefano Signorini · University Hospitals Parma Medical Center

Fausto Avanzini · University Hospitals Parma Medical Center

Fabrizio Pizzetti

Abstract

PTX3 is present in the intact myocardium, increases in the blood of patients with AMI, and disappears from damaged myocytes. We suggest that PTX3 is an early indicator of myocyte irreversible injury in ischemic cardiomyopathy.

Topics & Keywords

Biomarkers in Disease Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 102, Issue 6, pp. 636-641

DOI: 10.1161/01.cir.102.6.636

Field-Weighted Citation Impact: 2.05