New miRNA Profiles Accurately Distinguish Renal Cell Carcinomas and Upper Tract Urothelial Carcinomas from the Normal Kidney

201450 citationsJournal Articlegold Open Access

Authors

Apostolos Zaravinos · University of Cyprus

George Ι. Lambrou · National and Kapodistrian University of Athens

Nikos Mourmouras · General Hospital Asklepieio Voulas

Patroklos Katafygiotis · General Hospital Asklepieio Voulas

Gregory Papagregoriou · University of Cyprus

Κρινιώ Γιαννίκου · National and Kapodistrian University of Athens

Dimitris Delakas

Abstract

We identified novel miRNAs specific for each RCC subtype and UT-UC, we investigated their putative targets, the networks and pathways in which they participate and we functionally verified the true targets of the top deregulated miRNAs.

Topics & Keywords

Renal cell carcinoma treatment MicroRNA in disease regulation Renal and related cancers

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: PLoS ONE

Volume 9, Issue 3, pp. e91646-e91646

DOI: 10.1371/journal.pone.0091646

Field-Weighted Citation Impact: 4.81