Soft‐tissue sarcomas in children and adolescents with neurofibromatosis type 1

2007126 citationsJournal Articlebronze Open Access

Authors

Andrea Ferrari · Fondazione IRCCS Istituto Nazionale dei Tumori

Gianni Bisogno · University of Padua

Alessandra Macaluso · Azienda di Rilievo Nazionale ed Alta Specializzazione

Michela Casanova · Fondazione IRCCS Istituto Nazionale dei Tumori

Paolo D’Angelo · Azienda di Rilievo Nazionale ed Alta Specializzazione

Paolo Pierani · Fondazione Ospedale Salesi

Ilaria Zanetti

Abstract

The occurrence of STS in pediatric patients with NF1 syndrome in Italy is discussed, confirming that NF1 patients have a high risk of developing STS, and particularly MPNST, often with an aggressive clinical presentation and poor outcome. Cases of RMS tended to have particular features (early age, embryonal histotype, genitourinary site) and their outcome seemed to resemble that of the general RMS population.

Topics & Keywords

Neurofibromatosis and Schwannoma Cases Sarcoma Diagnosis and Treatment Soft tissue tumor case studies

Publication Details

Published in: Cancer

Volume 109, Issue 7, pp. 1406-1412

DOI: 10.1002/cncr.22533

Field-Weighted Citation Impact: 6.31

Command Palette

Soft‐tissue sarcomas in children and adolescents with neurofibromatosis type 1

Authors

Abstract

Topics & Keywords

Publication Details