Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

20143,255 citationsJournal Articlegold Open Access

Authors

Ying Yang · State Key Laboratory of Diagnosis and Treatment of Infectious Diseases

Shuping Li · Zhejiang University

Qiao Yang · Zhejiang University

Yu Shi · Zhejiang University

Min Zheng · Zhejiang University

Yanning Liu · Zhejiang University

Feng Chen ·

Abstract

Res can block the inflammatory effects induced by LPS in RAW264.7 cells. Down-regulation of HMGB expression may be one of the mechanisms of action of Res. Res may also influence TLR4 expression in the HMGB1-TLR4 signaling pathway.

Topics & Keywords

Advanced Glycation End Products research Heme Oxygenase-1 and Carbon Monoxide Immune Response and Inflammation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 33, Issue 5, pp. 1283-1292

DOI: 10.1159/000358696

Field-Weighted Citation Impact: 208.31