Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay

2010146 citationsJournal Article

Authors

Julieta M. Panzica‐Kelly · Bristol-Myers Squibb (Germany)

Cindy Zhang · Bristol-Myers Squibb (United States)

Tracy L. Danberry · Bristol-Myers Squibb (United States)

Annette Flood

Judiann W. DeLan

Kimberly Brannen · Bristol-Myers Squibb (United States)

Karen Augustine‐Rauch · Bristol-Myers Squibb (United States)

Abstract

To this end, the morphological score system provides information of tissue-specific teratogenicity that has been found to have good concordance with structures found affected in vivo and can also be used to rank compounds based on the severity of malformations.

Topics & Keywords

Zebrafish Biomedical Research Applications Assisted Reproductive Technology and Twin Pregnancy Congenital heart defects research

Publication Details

Published in: Birth Defects Research Part B Developmental and Reproductive Toxicology

Volume 89, Issue 5, pp. 382-395

DOI: 10.1002/bdrb.20260

Field-Weighted Citation Impact: 2.00

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Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay

Authors

Abstract

Topics & Keywords

Publication Details