The Relationship of Blood Product Ratio to Mortality: Survival Benefit or Survival Bias?

2009389 citationsJournal Article

Authors

Christopher W. Snyder · University of Alabama at Birmingham

Jordan A. Weinberg · University of Alabama at Birmingham

Gerald McGwin · University of Alabama

Sherry M. Melton · University of Alabama

Richard L. George · University of Alabama at Birmingham

Donald A. Reiff · University of Alabama

James M. Cross

Abstract

Similar to previous studies, an association between higher FFP:PRBC ratios at 24 hours and improved survival was observed. However, after adjustment for survival bias in the analysis, the association was no longer statistically significant. Prospective trials are necessary to evaluate whether hemostatic resuscitation is clinically beneficial.

Topics & Keywords

Trauma, Hemostasis, Coagulopathy, Resuscitation Blood donation and transfusion practices Renal function and acid-base balance

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Trauma: Injury, Infection, and Critical Care

Volume 66, Issue 2, pp. 358-364

DOI: 10.1097/ta.0b013e318196c3ac

Field-Weighted Citation Impact: 29.27