Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts

20031,400 citationsJournal Article

Authors

Abstract

Michael reaction of malonates to nitroolefins with chiral bifunctional organocatalysts, bearing both a thiourea and tertiary amino group, afforded Michael adducts with high yields and enantioselectivities (up to 95%, up to 93% ee).

Topics & Keywords

Asymmetric Synthesis and Catalysis Analytical Chemistry and Chromatography Axial and Atropisomeric Chirality Synthesis

Publication Details

Published in: Journal of the American Chemical Society

Volume 125, Issue 42, pp. 12672-12673

DOI: 10.1021/ja036972z

Field-Weighted Citation Impact: 27.11

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Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts

Authors

Abstract

Topics & Keywords

Publication Details