PAMAM-Lys, a Novel Vaccine Delivery Vector, Enhances the Protective Effects of the SjC23 DNA Vaccine against Schistosoma japonicum Infection

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Authors

Xiaoting Wang · First Affiliated Hospital of Soochow University

Yang Dai · Jiangsu Institute of Parasitic Diseases

Zhao Song · Jiangsu Institute of Parasitic Diseases

Jianxia Tang · Jiangsu Institute of Parasitic Diseases

Hongjun Li · Jiangsu Institute of Parasitic Diseases

Yuntian Xing · Jiangsu Institute of Parasitic Diseases

Guoli Qu

Abstract

Lysine-modified PAMAM-Lys is an excellent vector. PAMAM-Lys may enhance the immunoreactivity of DNA vaccine and increase the protective effect of the SjC23 DNA vaccine against S. japonicum infection.

Topics & Keywords

Parasites and Host Interactions Research on Leishmaniasis Studies Hepatitis Viruses Studies and Epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 9, Issue 1, pp. e86578-e86578

DOI: 10.1371/journal.pone.0086578

Field-Weighted Citation Impact: 1.91