SLC11A1 (NRAMP1) Polymorphisms and Tuberculosis Susceptibility: Updated Systematic Review and Meta-Analysis

2011120 citationsReviewgold Open Access

Authors

XiangWei Li · Chinese Academy of Medical Sciences & Peking Union Medical College

Yu Yang · Chinese Academy of Medical Sciences & Peking Union Medical College

Feng Zhou · Chinese Academy of Medical Sciences & Peking Union Medical College

Yunzhi Zhang · Shanghai Public Health Clinical Center

Hongzhou Lu · Shanghai Public Health Clinical Center

Qi Jin · Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

The association between SLC11A1 polymorphisms and tuberculosis susceptibility observed in our analyses supports the hypothesis that NRAMP1 might play an important role in the host defense to the development of tuberculosis.

Topics & Keywords

Tuberculosis Research and Epidemiology Pneumocystis jirovecii pneumonia detection and treatment Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 6, Issue 1, pp. e15831-e15831

DOI: 10.1371/journal.pone.0015831

Field-Weighted Citation Impact: 6.62