SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

2010203 citationsJournal Articlegold Open Access

Authors

Bernd Schmidt · University Hospital in Halle

Volker Liebenberg

Dimo Dietrich · Epigenomics (Germany)

Thomas Schlegel · Epigenomics (Germany)

Christoph Kneip

Anke Seegebarth · Bavarian Nordic (Germany)

Nadja Flemming · Epigenomics (Germany)

Stefanie Seemann

Abstract

Hypermethylation of SHOX2 in bronchial aspirates appears to be a clinically useful tumor marker for identifying subjects with lung carcinoma, especially if histological and cytological findings after bronchoscopy are ambiguous.

Topics & Keywords

Epigenetics and DNA Methylation Tracheal and airway disorders Neonatal Respiratory Health Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Cancer

Volume 10, Issue 1, pp. 600-600

DOI: 10.1186/1471-2407-10-600

Field-Weighted Citation Impact: 4.07