Hemagglutination inhibiting antibodies and protection against seasonal and pandemic influenza infection

201449 citationsJournal Articlehybrid Open Access

Authors

Annette Fox · The University of Melbourne

Lê Quynh · National Institute Of Hygiene And Epidemiology

Le Thị Thanh · National Institute Of Hygiene And Epidemiology

Marcel Wolbers · Oxford University Clinical Research Unit

Nguyễn Lê Khánh Hằng · National Institute Of Hygiene And Epidemiology

Phạm Quang Thái · National Institute Of Hygiene And Epidemiology

Nguyen Thi Thu Yen

Abstract

While H1N1 immunity was apparent with increasing age and prior infection, the effect of pre-season HI titer was at best small, and weak for H1N1 compared to H3N2 and B. Antibodies targeting non-HI epitopes may have been more important mediators of infection-neutralizing immunity for H1N1 compared to other subtypes in this setting.

Topics & Keywords

Influenza Virus Research Studies Respiratory viral infections research Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Infection

Volume 70, Issue 2, pp. 187-196

DOI: 10.1016/j.jinf.2014.09.003

Field-Weighted Citation Impact: 3.22