DNA methylation status is more reliable than gene expression at detecting cancer in prostate biopsy

201477 citationsJournal Articlehybrid Open Access

Authors

Agnieszka Paziewska

Michalina Dąbrowska · The Maria Sklodowska-Curie National Research Institute of Oncology

Krzysztof Goryca · The Maria Sklodowska-Curie National Research Institute of Oncology

Artur A. Antoniewicz

Jakub Dobruch

Michał Mikuła · The Maria Sklodowska-Curie National Research Institute of Oncology

Dorota Jarosz

Łukasz Zapała

Andrzej Borówka

Abstract

DNA methylation-based biomarkers reflect the prostate malignancy and might be useful in supporting clinical decisions for suspected PCa following an initial negative prostate biopsy.

Topics & Keywords

Prostate Cancer Diagnosis and Treatment Prostate Cancer Treatment and Research Urological Disorders and Treatments

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: British Journal of Cancer

Volume 111, Issue 4, pp. 781-789

DOI: 10.1038/bjc.2014.337

Field-Weighted Citation Impact: 6.05