The plasma lipidomic signature of nonalcoholic steatohepatitis†‡

2009643 citationsJournal Article

Authors

Prem Puri · Virginia Commonwealth University Medical Center

Michelle M. Wiest

Onpan Cheung · Virginia Commonwealth University Medical Center

Faridoddin Mirshahi · Virginia Commonwealth University Medical Center

Carol Sargeant · Virginia Commonwealth University Medical Center

Hae‐Ki Min · Virginia Commonwealth University Medical Center

Melissa J. Contos · Virginia Commonwealth University Medical Center

Abstract

Although increased lipogenesis, desaturases, and LOX activities characterize NAFL and NASH, impaired peroxisomal polyunsaturated fatty acid (PUFA) metabolism and nonenzymatic oxidation is associated with progression to NASH.

Topics & Keywords

Liver Disease Diagnosis and Treatment Diet, Metabolism, and Disease Lipid metabolism and biosynthesis

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Hepatology

Volume 50, Issue 6, pp. 1827-1838

DOI: 10.1002/hep.23229

Field-Weighted Citation Impact: 15.57