Lipoprotein Metabolism in Japanese Centenarians: Effects of Apolipoprotein E Polymorphism and Nutritional Status

200150 citationsJournal Article

Authors

Yasumichi Arai · Keio University

Nobuyoshi Hirose · Keio University

Susumu Nakazawa · Keio University

K. Yamamura · Keio University

K Shimizu · Keio University

Michiyo Takayama · Keio University

Yoshinori Ebihara · Keio University

Abstract

Low levels of apo B-containing lipoproteins attributable to a genetic cause may be advantageous for longevity. Lipoprotein profiles in centenarians were consistently related to the subjects' nutritional status, inflammation markers, and apo E polymorphisms. The results provide evidence for the importance of maintaining nutritional status in the very old.

Topics & Keywords

Antioxidant Activity and Oxidative Stress Diabetes, Cardiovascular Risks, and Lipoproteins Adipose Tissue and Metabolism

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Journal of the American Geriatrics Society

Volume 49, Issue 11, pp. 1434-1441

DOI: 10.1046/j.1532-5415.2001.4911234.x

Field-Weighted Citation Impact: 0.53