Decreased Srcasm expression in hyperproliferative cutaneous lesions

200811 citationsJournal Articlegreen Open Access

Authors

Marc C. Meulener · University of Pennsylvania

Elias E. Ayli · University of Pennsylvania

Rosalie Elenitsas · University of Pennsylvania

John T. Seykora · University of Pennsylvania

Abstract

Our results support the hypothesis that Srcasm protein levels are decreased in the hyperproliferative keratinocytes found in SKs and BCCs. Increased Srcasm protein levels are detected in keratinocytes undergoing differentiation. Decreased Srcasm levels may be part of the pathophysiologic mechanism in cutaneous lesions, exhibiting keratinocyte hyperproliferation.

Topics & Keywords

Sarcoma Diagnosis and Treatment Hippo pathway signaling and YAP/TAZ Histiocytic Disorders and Treatments

Publication Details

Published in: Journal of Cutaneous Pathology

Volume 36, Issue 3, pp. 291-295

DOI: 10.1111/j.1600-0560.2008.01035.x

Field-Weighted Citation Impact: 0.76

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Decreased Srcasm expression in hyperproliferative cutaneous lesions

Authors

Abstract

Topics & Keywords

Publication Details