Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice

2014178 citationsJournal Articlehybrid Open Access

Authors

Barbara Budzyńska · Medical University of Lublin

Anna Boguszewska‐Czubara · Medical University of Lublin

Marta Kruk-Słomka · Medical University of Lublin

Krystyna Skalicka‐Woźniak · Medical University of Lublin

Agnieszka Michalak · Medical University of Lublin

Irena Musik · Medical University of Lublin

Grażyna Biała

Abstract

These results demonstrate that imperatorin may offer protection against scopolamine-induced memory impairments and possesses antioxidant properties, thus after further preclinical and clinical studies this compound may provide an interesting approach in pharmacotherapy, as well as prophylactics of AD.

Topics & Keywords

Plant chemical constituents analysis Nicotinic Acetylcholine Receptors Study Alkaloids: synthesis and pharmacology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Psychopharmacology

Volume 232, Issue 5, pp. 931-942

DOI: 10.1007/s00213-014-3728-6

Field-Weighted Citation Impact: 15.39