Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study

2005146 citationsJournal Article

Authors

Todd Hulgan · Office of Infectious Diseases

David W. Haas · Center for Human Genetics

Jonathan L. Haines · Center for Human Genetics

Marylyn D. Ritchie · Center for Human Genetics

Gregory K. Robbins · Harvard University

Robert W. Shafer · Stanford University

David B. Clifford ·

Abstract

A common European mitochondrial haplogroup may predict NRTI-associated peripheral neuropathy. Future studies should validate this relationship, and evaluate non-European mitochondrial haplogroups and other NRTI toxicities.

Topics & Keywords

HIV Research and Treatment HIV/AIDS drug development and treatment HIV-related health complications and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: AIDS

Volume 19, Issue 13, pp. 1341-1349

DOI: 10.1097/01.aids.0000180786.02930.a1

Field-Weighted Citation Impact: 4.42