Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents

20071,622 citationsJournal Articlebronze Open Access

Authors

Gregg W. Stone · Columbia University Irving Medical Center

Jeffrey W. Moses · Columbia University Irving Medical Center

Stephen G. Ellis · Cleveland Clinic

Joachim Schöfer · Universität Hamburg

Keith D. Dawkins · University Hospital Southampton NHS Foundation Trust

Marie-Claude Morice · Institut Cardiovasculaire Paris Sud

Antonio Colombo

Abstract

Stent thrombosis after 1 year was more common with both sirolimus-eluting stents and paclitaxel-eluting stents than with bare-metal stents. Both drug-eluting stents were associated with a marked reduction in target-lesion revascularization. There were no significant differences in the cumulative rates of death or myocardial infarction at 4 years.

Topics & Keywords

Coronary Interventions and Diagnostics Antiplatelet Therapy and Cardiovascular Diseases Cardiac Valve Diseases and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 356, Issue 10, pp. 998-1008

DOI: 10.1056/nejmoa067193

Field-Weighted Citation Impact: 220.19