Iron-Overload–Related Disease in<i>HFE</i>Hereditary Hemochromatosis

2008718 citationsJournal Articlebronze Open Access

Authors

Katrina J. Allen · University of Melbourne

Lyle C. Gurrin

Clare C. Constantine

Nicholas J. Osborne · Murdoch Children's Research Institute

Martin B. Delatycki · University of Melbourne

Amanda Nicoll · The Royal Melbourne Hospital

Christine E. McLaren · University of California, Irvine

Melanie Bahlo

Abstract

In persons who are homozygous for the C282Y mutation, iron-overload-related disease developed in a substantial proportion of men but in a small proportion of women.

Topics & Keywords

Iron Metabolism and Disorders Hemoglobinopathies and Related Disorders Trace Elements in Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 358, Issue 3, pp. 221-230

DOI: 10.1056/nejmoa073286

Field-Weighted Citation Impact: 37.18

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