Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases

2012482 citationsReview

Authors

Erwin W. Gelfand · University of Colorado Denver

Abstract

The author reviews the many proposed mechanisms by which intravenous immune globulin may exert its antiinflammatory and autoimmunity-inhibiting clinical effects. No single mechanism can explain its activity in diseases with diverse pathophysiological pathways.

Topics & Keywords

Platelet Disorders and Treatments Immunodeficiency and Autoimmune Disorders Blood disorders and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 367, Issue 21, pp. 2015-2025

DOI: 10.1056/nejmra1009433

Field-Weighted Citation Impact: 26.18