Effect of preoperative Cox‐II‐selective NSAIDs (coxibs) on postoperative outcomes: A systematic review of randomized studies

Preoperative coxibs had clear benefits in terms of reduced postoperative pain, analgesic consumption and patient satisfaction compared with placebo. Effects on postoperative nausea and vomiting remain uncertain, as do those on recovery from surgery or economic benefit. Future trials should be larger and more pragmatic in nature.