Novel One-Pot, Three-Component Synthesis of New 2-Alkyl-5-aryl-(1<i>H</i>)-pyrrole-4-ol in Water

2008108 citationsJournal Article

Authors

Behzad Khalili · Sharif University of Technology

Pedram Jajarmi · Sharif University of Technology

Bagher Eftekhari‐Sis · Sabzevar University of New Technology

Mohammed M. Hashemi · Sharif University of Technology

Abstract

New 2-alkyl-5-aryl-(1H)-pyrrole-4-ol derivatives were synthesized via three-component reaction of beta-dicarbonyl compounds with arylglyoxals in the presence of ammonium acetate in water at room temperature.

Topics & Keywords

Synthesis and Characterization of Pyrroles Multicomponent Synthesis of Heterocycles Porphyrin and Phthalocyanine Chemistry

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: The Journal of Organic Chemistry

Volume 73, Issue 6, pp. 2090-2095

DOI: 10.1021/jo702385n

Field-Weighted Citation Impact: 4.81