Variation in Human Recombination Rates and Its Genetic Determinants

2011125 citationsJournal Articlegold Open Access

Authors

Adi Fledel-Alon · University of Chicago

Ellen M. Leffler · University of Chicago

Yongtao Guan · University of Chicago

Matthew Stephens · University of Chicago

Graham Coop · University of California, Davis

Molly Przeworski · University of Chicago

Abstract

These findings suggest that variation at broad and fine scales is largely separable and that, beyond three known loci, there is no evidence for common variation with large effects on recombination phenotypes.

Topics & Keywords

DNA Repair Mechanisms Genetic Mapping and Diversity in Plants and Animals Evolution and Genetic Dynamics

Publication Details

Published in: PLoS ONE

Volume 6, Issue 6, pp. e20321-e20321

DOI: 10.1371/journal.pone.0020321

Field-Weighted Citation Impact: 5.32

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Variation in Human Recombination Rates and Its Genetic Determinants

Authors

Abstract

Topics & Keywords

Publication Details