Serotyping for Homotransplantation

196841 citationsJournal Article

Authors

Paul I. Terasaki · University of California, Los Angeles

M. R. Mickey · University of California, Los Angeles

D. P. Singal · University of California, Los Angeles

Kamal K. Mittal · University of California, Los Angeles

Ramon Patel · University of California, Los Angeles

Abstract

TWO recent developments have greatly changed the outlook of histocompatibility testing in clinical kidney transplantation. The first is the dramatic advances made in the area of serologic typing of leukocytes. The Third Histocompatibility Testing Workshop held in Torino, Italy, in June, 1967, showed that many laboratories are now identifying the same leukocyte antigens with considerable precision and that these antigens for the most part belong to a single complex system called HL-A.1 The second development has been the accumulation of evidence that these antigens function as histocompatibility antigens influencing kidney function, renal histology2 and survival of transplants3 from related donors. . . .

Topics & Keywords

Renal Transplantation Outcomes and Treatments Blood groups and transfusion Organ Transplantation Techniques and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 279, Issue 20, pp. 1101-1103

DOI: 10.1056/nejm196811142792007

Field-Weighted Citation Impact: 9.08