Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis

2008522 citationsJournal Articlegreen Open Access

Authors

Martina Korfei · Justus-Liebig-Universität Gießen

Clemens Ruppert · Justus-Liebig-Universität Gießen

Poornima Mahavadi · Justus-Liebig-Universität Gießen

Ingrid Henneke · Justus-Liebig-Universität Gießen

Philipp Markart · Justus-Liebig-Universität Gießen

Miriam Koch · Justus-Liebig-Universität Gießen

György Láng

Abstract

Severe ER stress response in the AECIIs of patients with sporadic IPF may underlie the apoptosis of this cell type and development of fibrosis in this disease.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Endoplasmic Reticulum Stress and Disease Autophagy in Disease and Therapy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 178, Issue 8, pp. 838-846

DOI: 10.1164/rccm.200802-313oc

Field-Weighted Citation Impact: 19.97