Coronary Artery Disease and Polymorphisms in a Receptor Mediating Shear Stress–Dependent Platelet Activation

1997109 citationsJournal Article

Authors

Mitsuru Murata · Keio University

Yumiko Matsubara · Keio University

Koichi Kawano · Keio University

Takeru Zama · Keio University

Nobuo Aoki · Keio University

Hideaki Yoshino · Keio University

Gentaro Watanabe · Keio University

Abstract

This study suggests that the presence of the Met allele in GP Ib alpha is a risk factor for the prevalence and severity of CAD in individuals aged < or = 60 years. The results need to be confirmed in a large-scale study of incident case subjects and matching control subjects.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Antiplatelet Therapy and Cardiovascular Diseases Blood properties and coagulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 96, Issue 10, pp. 3281-3286

DOI: 10.1161/01.cir.96.10.3281

Field-Weighted Citation Impact: 6.44