The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients

201521 citationsJournal Articlehybrid Open Access

Authors

Nasser Rizk · Qatar University

Ayman El‐Menyar · Research Institute of Ophthalmology

Huda Egue · Qatar University

Idil Souleman Wais · Qatar University

Hissa Mohamed Baluli · Qatar University

Khalid Alali · Qatar University

Fathi Farag ·

Abstract

Polymorphisms rs646776 and rs599839 of locus 1p13.3 were significantly associated with LDL-C and other lipid parameters. In addition, the G-allele carriers of variant rs599839 had a significant protective effect against the atherosclerosis.

Topics & Keywords

Lipoproteins and Cardiovascular Health Genetic Associations and Epidemiology RNA Research and Splicing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BioMed Research International

Volume 2015, pp. 1-12

DOI: 10.1155/2015/678924

Field-Weighted Citation Impact: 0.89