Randomized, Double-blind Comparison of Hirulog Versus Heparin in Patients Receiving Streptokinase and Aspirin for Acute Myocardial Infarction (HERO)

1997231 citationsJournal Article

Authors

Harvey D. White · Royal Adelaide Hospital

Philip E. Aylward · Royal Victoria Eye and Ear Hospital

M Frey · University of Oxford

A.A.J. Adgey · University of Oxford

Ravi Nair · University of Oxford

W. Stewart Hillis · University Hospitals of Cleveland

Yoseph Shalev ·

Abstract

Hirulog was more effective than heparin in producing early patency in patients treated with aspirin and streptokinase without increasing the risk of major bleeding. Direct thrombin inhibition may improve clinical outcome.

Topics & Keywords

Acute Myocardial Infarction Research Atrial Fibrillation Management and Outcomes Venous Thromboembolism Diagnosis and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 96, Issue 7, pp. 2155-2161

DOI: 10.1161/01.cir.96.7.2155

Field-Weighted Citation Impact: 19.28