Increased Negative Impact of Donor HLA-Specific Together With Non-HLA–Specific Antibodies on Graft Outcome

2013119 citationsJournal Article

Authors

Nancy L. Reinsmoen · Cedars-Sinai Medical Center

Chih‐Hung Lai · Cedars-Sinai Medical Center

James Mirocha

Kai Cao · The University of Texas MD Anderson Cancer Center

Geraldine Ong · Cedars-Sinai Medical Center

Mehrnoush Naim · Cedars-Sinai Medical Center

Qi Wang · Cedars-Sinai Medical Center

Abstract

These results show the increased negative impact of dnDSA and AT1R-ab on freedom from AMR and/or CMR and an increased hazard ratio when both parameters are considered. Both HLA- and non-HLA-specific antibodies seem to impact graft outcome in heart transplantation.

Topics & Keywords

Renal Transplantation Outcomes and Treatments Transplantation: Methods and Outcomes Organ Transplantation Techniques and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Transplantation

Volume 97, Issue 5, pp. 595-601

DOI: 10.1097/01.tp.0000436927.08026.a8

Field-Weighted Citation Impact: 7.30