Efficacy and Safety of Antifungal Additives in Optisol-GS Corneal Storage Medium

201472 citationsJournal Article

Authors

Noelle Layer · University of California, San Francisco

Vicky Cevallos · San Francisco Foundation

Andrew J. Maxwell · SightLife

Caroline K. Hoover · SightLife

Jeremy D. Keenan · San Francisco Foundation

Bennie H. Jeng · University of California, San Francisco

Abstract

The addition of amphotericin B to Optisol-GS may significantly improve activity against contamination with Candida species, the primary cause of fungal infection after corneal transplantation. This study found significant endothelial toxic effects at the maximal concentration of amphotericin B.

Topics & Keywords

Ocular Infections and Treatments Ocular Surface and Contact Lens Corneal Surgery and Treatments

Publication Details

Published in: JAMA Ophthalmology

Volume 132, Issue 7, pp. 832-832

DOI: 10.1001/jamaophthalmol.2014.397

Field-Weighted Citation Impact: 3.70

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Efficacy and Safety of Antifungal Additives in Optisol-GS Corneal Storage Medium

Authors

Abstract

Topics & Keywords

Publication Details