Intestinal Polyposis and Pigmentation of the Lip

THE strange association of intestinal polyposis and melanotic spots of the oral mucous membranes was unrecognized in the English and American literature as a syndrome of diagnostic significance until recently.With their classic description in 1949, Jeghers and his co-workers1 alerted the medical profession to the puzzling association of these two rare conditions. These authors exhaustively reviewed previous articles in the world literature. Subsequent reports through January, 1954, have been reviewed.2 An additional case has been reported by Bruwer, Bargen and Kier-land,3 who suggested the eponym, Peutz-Jeghers syndrome, for the condition, since Peutz4 made the original observation and Jeghers et . . .