Congenital diaphragmatic hernia: US diagnosis prior to 22 weeks gestation.

Two cases of congenital diaphragmatic hernia diagnosed sonographically in utero at 18 and 21 weeks gestation are described. In previous reports, this diagnosis has been made at 28 weeks or more. Recognition of this severe abnormality in the second trimester affords two options. The parents can interrupt the pregnancy, or a surgical attempt at correction in utero may be possible and be early enough to allow adequate lung development to take place.