Serum markers of oxidative stress and severity of diabetic retinopathy.

2000163 citationsJournal Article

Authors

M. Elizabeth Hartnett · Harvard University

Ron Stratton · Massachusetts Eye and Ear Infirmary

Roy Browne · University at Buffalo, State University of New York

B. A. Rosner · Harvard University

Richard J. Lanham · Buffalo State University

David T. Armstrong · University at Buffalo, State University of New York

Abstract

Increased levels of TBARS and decreased levels of SOD and GSH-Px were found in diabetic patients compared with those in control subjects, but no significant associations were found between the levels of these substances and severity of retinopathy When duration and type of diabetes and serum HbA1 levels were taken into account, only visual acuity remained associated with more severe retinopathy.

Topics & Keywords

Retinal Diseases and Treatments Advanced Glycation End Products research Glaucoma and retinal disorders

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Diabetes Care

Volume 23, Issue 2, pp. 234-240

DOI: 10.2337/diacare.23.2.234

Field-Weighted Citation Impact: 5.97