Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

2010402 citationsJournal Articlegold Open Access

Authors

Claudio Donati · Novartis (Italy)

N. Luisa Hiller · Allegheny-Singer Research Institute

Hervé Tettelin · University of Maryland, Baltimore

Alessandro Muzzi · Newron Pharmaceuticals (Italy)

Nicholas J. Croucher · Wellcome Sanger Institute

Samuel V. Angiuoli · University of Maryland, Baltimore

Marco R. Oggioni

Abstract

Genetic exchange with related species sharing the same ecological niche is the main mechanism of evolution of S. pneumoniae. The open pan-genome guarantees the species a quick and economical response to diverse environments.

Topics & Keywords

Pneumonia and Respiratory Infections Streptococcal Infections and Treatments Infective Endocarditis Diagnosis and Management

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Genome biology

Volume 11, Issue 10, pp. R107-R107

DOI: 10.1186/gb-2010-11-10-r107

Field-Weighted Citation Impact: 16.32

Command Palette