Rickettsia Phylogenomics: Unwinding the Intricacies of Obligate Intracellular Life

2008221 citationsJournal Articlegold Open Access

Authors

Joseph J. Gillespie · Virginia Tech

Kelly P. Williams · Virginia Tech

Maulik Shukla · Virginia Tech

Eric E. Snyder · Virginia Tech

Eric K. Nordberg · Virginia Tech

Shane M. Ceraul · University of Maryland, Baltimore

Chitti Dharmanolla ·

Abstract

Collectively, we determined the relative conservation and distribution of 14354 predicted ORFs from 10 rickettsial genomes across robust phylogeny estimation. The data, available at PATRIC (PathoSystems Resource Integration Center), provide novel information for unwinding the intricacies associated with Rickettsia pathogenesis, expanding the range of potential diagnostic, vaccine and therapeutic targets.

Topics & Keywords

Vector-borne infectious diseases Insect symbiosis and bacterial influences Genomics and Phylogenetic Studies

Publication Details

Published in: PLoS ONE

Volume 3, Issue 4, pp. e2018-e2018

DOI: 10.1371/journal.pone.0002018

Field-Weighted Citation Impact: 6.03

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Rickettsia Phylogenomics: Unwinding the Intricacies of Obligate Intracellular Life

Authors

Abstract

Topics & Keywords

Publication Details