The Importance of Measuring Ionized Calcium in Characterizing Calcium Status and Diagnosing Primary Hyperparathyroidism

201293 citationsJournal Articlebronze Open Access

Authors

Gregory S Y Ong · Pathwest Laboratory Medicine

John P. Walsh · University of Western Australia

Bronwyn Stuckey · Keogh Institute for Medical Research

Suzanne J. Brown · Diabetes Australia

Enrico Rossi · Pathwest Laboratory Medicine

Jennifer L. Ng · Pathwest Laboratory Medicine

Hieu Nguyen

Abstract

In abnormal calcium states, tCa frequently disagrees with iCa in classifying calcium status. Histologically proven parathyroid disease can present with isolated ionized hypercalcemia. Measurement of iCa is required to accurately assess calcium status and improve diagnostic accuracy.

Topics & Keywords

Parathyroid Disorders and Treatments Bone health and treatments Medical Imaging and Pathology Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 97, Issue 9, pp. 3138-3145

DOI: 10.1210/jc.2012-1429

Field-Weighted Citation Impact: 3.77