Intracoronary Angiotensin II Potentiates Coronary Sympathetic Vasoconstriction in Humans

199760 citationsJournal Article

Authors

Antonio Saino · EMO GVM Centro Cuore Columbus

G. Pomidossi · EMO GVM Centro Cuore Columbus

R Perondi · EMO GVM Centro Cuore Columbus

R Valentini · EMO GVM Centro Cuore Columbus

Alberto Rimini · EMO GVM Centro Cuore Columbus

Lucia Di Francesco · EMO GVM Centro Cuore Columbus

Giuseppe Mancia

Abstract

Ang II markedly enhances sympathetic influences on coronary circulation in humans, presumably by acting at the arteriolar level. This may explain the blunting effect of ACE inhibition on sympathetic coronary vasoconstriction in patients with coronary artery disease.

Topics & Keywords

Heart Rate Variability and Autonomic Control Blood Pressure and Hypertension Studies Pulmonary Hypertension Research and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 96, Issue 1, pp. 148-153

DOI: 10.1161/01.cir.96.1.148

Field-Weighted Citation Impact: 4.66