Convergence of genetic influences in comorbidity

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Authors

Richard C. McEachin · University of Michigan–Ann Arbor

Keerthi Sannareddy · University of Michigan–Ann Arbor

James D. Cavalcoli · University of Michigan–Ann Arbor

Alla Karnovsky · University of Michigan–Ann Arbor

Jacqueline M. Vink · Vrije Universiteit Amsterdam

Maureen A. Sartor · University of Michigan–Ann Arbor

Abstract

ModRP is a novel approach to identifying pleiotropic genetic influences on comorbid complex diseases. It can be used to assess association for related phenotypes where raw data is unavailable or inappropriate for analysis using other approaches. The method is conceptually simple and produces statistically significant, biologically relevant results.

Topics & Keywords

Genetic Associations and Epidemiology Bioinformatics and Genomic Networks Alcohol Consumption and Health Effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Bioinformatics

Volume 13, Issue S2, pp. S8-S8

DOI: 10.1186/1471-2105-13-s2-s8

Field-Weighted Citation Impact: 0.62