Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells

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Authors

Gwang Hun Park · Andong National University

Jae Ho Park · Jungwon University

Hun Min Song · Andong National University

Hyun Ji Eo · Andong National University

Mi Kyoung Kim · Andong National University

Jin Wook Lee · Gyeongbuk Marine Bio-Industry Research Institute

Man Hyo Lee ·

Abstract

These findings suggest that the reduction of cell viability and apoptosis by GL may be a result of ATF3 promoter activation and subsequent increase of ATF3 expression through ERK1/2 activation in human colorectal cancer cells.

Topics & Keywords

Ginger and Zingiberaceae research MicroRNA in disease regulation Cancer Mechanisms and Therapy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Complementary and Alternative Medicine

Volume 14, Issue 1, pp. 408-408

DOI: 10.1186/1472-6882-14-408

Field-Weighted Citation Impact: 6.52