Immunosuppression in Patients with High-Grade Gliomas Treated with Radiation and Temozolomide

2011553 citationsJournal Articlebronze Open Access

Authors

Stuart A. Grossman · Cedars-Sinai Medical Center

Xiaobu Ye · Wake Forest University

Glenn J. Lesser · Johns Hopkins University

Andrew E. Sloan · Western University of Health Sciences

Hetty E. Carraway · Western University of Health Sciences

Serena Desideri · Western University of Health Sciences

Steven Piantadosi

Abstract

Severe reductions in CD4 counts in patients with newly diagnosed HGG treated with radiation and temozolomide treatment are common, treatment-related, long-lasting, and associated with early death from tumor progression.

Topics & Keywords

Glioma Diagnosis and Treatment Cancer Immunotherapy and Biomarkers Infectious Diseases and Tuberculosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 17, Issue 16, pp. 5473-5480

DOI: 10.1158/1078-0432.ccr-11-0774

Field-Weighted Citation Impact: 9.29