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Long-lasting Hyperalgesia Induced by Fentanyl in Rats

2000587 citationsJournal Article

Authors

Evelyne Célèrier · Galen University

Cyril Rivat · Galen University

Jun Yan · Sichuan University

Jean‐Paul Laulin · Université de Bordeaux

A. Larcher · Inserm

Pascal Reynier · Hôpital Cardiologique du Haut-Lévêque

Guy Simonnet · Inserm

Abstract

Fentanyl activates NMDA pain facilitatory processes, which oppose analgesia and lead to long-lasting enhancement in pain sensitivity.

Topics & Keywords

Pain Mechanisms and Treatments Neuroscience and Neuropharmacology Research Cancer, Stress, Anesthesia, and Immune Response

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 92, Issue 2, pp. 465-465

DOI: 10.1097/00000542-200002000-00029

Field-Weighted Citation Impact: 11.28

Long-lasting Hyperalgesia Induced by Fentanyl in Rats | Researchclopedia