Polymer Nanomicelles for Efficient Mucus Delivery and Antigen‐Specific High Mucosal Immunity

201340 citationsJournal Article

Authors

Young‐Woock Noh · Chungnam National University

Ji Hyun Hong · Chungnam National University

Sang‐Mu Shim · Korea Research Institute of Bioscience and Biotechnology

Hye Sun Park · Chungnam National University

Hee Ho Bae · Chungnam National University

E. K. RYU · Korea Basic Science Institute

Jung Hwan Hwang

Abstract

Micelles for mucosal immunity: A mucosal vaccine system based on γ-PGA nanomicelles and viral antigens was synthesized. The intranasal administration of the vaccine system induces a high immune response both in the humoral and cellular immunity (see picture).

Topics & Keywords

RNA Interference and Gene Delivery Advanced Drug Delivery Systems Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Angewandte Chemie International Edition

Volume 52, Issue 30, pp. 7684-7689

DOI: 10.1002/anie.201302881

Field-Weighted Citation Impact: 1.50