Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury

201559 citationsJournal Articlebronze Open Access

Authors

Yanlu Zhang

Michael Chopp · Oakland University

Yuling Meng · Henry Ford Health System

Zheng Gang Zhang · Henry Ford Hospital

Edith Doppler · EVER Neuro Pharma (Austria)

Stefan Winter · EVER Neuro Pharma (Austria)

Timothy Schallert · The University of Texas at Austin

Abstract

These results indicate that Cerebrolysin treatment of mTBI improves long-term cognitive function, and this improvement may be partially related to decreased brain APP accumulation and astrogliosis as well as increased neuroblasts and neurogenesis.

Topics & Keywords

Neurological Disorders and Treatments Traumatic Brain Injury and Neurovascular Disturbances Medicinal Plants and Bioactive Compounds

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of neurosurgery

Volume 122, Issue 4, pp. 843-855

DOI: 10.3171/2014.11.jns14271

Field-Weighted Citation Impact: 5.35