Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression

2010222 citationsJournal Articlegreen Open Access

Authors

Jun Wei · The University of Texas MD Anderson Cancer Center

Jason Barr · The University of Texas MD Anderson Cancer Center

Ling-Yuan Kong · The University of Texas MD Anderson Cancer Center

Yongtao Wang · The University of Texas MD Anderson Cancer Center

Adam Wu · The University of Texas MD Anderson Cancer Center

Amit Sharma · The University of Texas MD Anderson Cancer Center

Abstract

Cancer-initiating cells contribute to tumor evasion of the immunosurveillance and approaches that alter the differentiation state may have immunotherapeutic potential.

Topics & Keywords

Immunotherapy and Immune Responses CAR-T cell therapy research Phagocytosis and Immune Regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 16, Issue 2, pp. 461-473

DOI: 10.1158/1078-0432.ccr-09-1983

Field-Weighted Citation Impact: 11.01