Adipose Endocrine Function, Insulin-Like Growth Factor-1 Axis, and Exceptional Survival Beyond 100 Years of Age

200866 citationsJournal Articlebronze Open Access

Authors

Yuji Arai · Keio University

Mina Takayama · National Research Center for Preventive Medicine

Yasuyuki Gondo · Tokyo Metropolitan Institute of Gerontology

Hiroki Inagaki · Tokyo Metropolitan Institute of Gerontology

K. Yamamura · Mizuho (Japan)

S Nakazawa

Taro Kojima · RIKEN

Abstract

The results suggested that preservation of adipose endocrine function and the IGF-1 axis may be potentially important for maintaining health and function and promoting survival at an extremely old age.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism Metabolism, Diabetes, and Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journals of Gerontology Series A

Volume 63, Issue 11, pp. 1209-1218

DOI: 10.1093/gerona/63.11.1209

Field-Weighted Citation Impact: 4.51